FN Clarivate Analytics Web of Science
VR 1.0
PT J
AU Piber, D
   Nowacki, J
   Mueller, SC
   Wingenfeld, K
   Otte, C
AF Piber, Dominique
   Nowacki, Jan
   Mueller, Sven C.
   Wingenfeld, Katja
   Otte, Christian
TI Sex effects on spatial learning but not on spatial memory retrieval in
   healthy young adults
SO BEHAVIOURAL BRAIN RESEARCH
LA English
DT Article
DE Sex effects; Spatial learning; Spatial memory; Virtual morris water maze
ID MORRIS WATER MAZE; VIRTUAL NAVIGATION; GENDER-DIFFERENCES; ORIENTATION
   STRATEGIES; MENTAL ROTATION; VERBAL FLUENCY; TASK; HUMANS; WOMEN;
   PERFORMANCE
AB Objectives: Sex differences have been found in spatial learning and spatial memory, with several studies indicating that males outperform females. We tested in the virtual Morris Water Maze (vMWM) task, whether sex differences in spatial cognitive processes are attributable to differences in spatial learning or spatial memory retrieval in a large student sample.
   Methods: We tested 90 healthy students (45 women and 45 men) with a mean age of 23.5 years (SD = 3.5). Spatial learning and spatial memory retrieval were measured by using the vMWM task, during which participants had to search a virtual pool for a hidden platform, facilitated by visual cues surrounding the pool. Several learning trials assessed spatial learning, while a separate probe trial assessed spatial memory retrieval.
   Results: We found a significant sex effect during spatial learning, with males showing shorter latency and shorter path length, as compared to females (all p < 0.001). Yet, there was no significant sex effect in spatial memory retrieval (p = 0.615). Furthermore, post-hoc analyses revealed significant sex differences in spatial search strategies (p < 0.05), but no difference in the number of platform crossings (p = 0.375).
   Conclusion: Our results indicate that in healthy young adults, males show faster spatial learning in a virtual environment, as compared to females. Interestingly, we found no significant sex differences during spatial memory retrieval. Our study raises the question, whether men and women use different learning strategies, which nevertheless result in equal performances of spatial memory retrieval.
C1 [Piber, Dominique; Nowacki, Jan; Wingenfeld, Katja; Otte, Christian] Charite Univ Med Berlin, Dept Psychiat, Berlin, Germany.
   [Mueller, Sven C.] Univ Ghent, Dept Expt Clin & Hlth Psychol, Ghent, Belgium.
RP Piber, D (reprint author), Charite Univ Med Berlin, Dept Psychiat, Campus Benjamin Franklin, Hindenburgdamm 30, D-12203 Berlin, Germany.
EM dominique.piber@charite.de
CR Astur RS, 2016, BEHAV BRAIN RES, V308, P236, DOI 10.1016/j.bbr.2016.04.037
   Astur RS, 2004, BEHAV BRAIN RES, V151, P103, DOI 10.1016/j.bbr.2003.08.024
   Astur RS, 2002, BEHAV BRAIN RES, V132, P77, DOI 10.1016/S0166-4328(01)00399-0
   Astur RS, 1998, BEHAV BRAIN RES, V93, P185, DOI 10.1016/S0166-4328(98)00019-9
   Baldi E, 2005, NEUROSCI LETT, V378, P176, DOI 10.1016/j.neulet.2004.12.029
   Blokland A, 2006, BEHAV BRAIN RES, V171, P216, DOI 10.1016/j.bbr.2006.03.033
   Bohbot VD, 2012, FRONT AGING NEUROSCI, V4, DOI 10.3389/fnagi.2012.00028
   Burke A, 2012, HUM NATURE-INT BIOS, V23, P133, DOI 10.1007/s12110-012-9140-1
   Burkitt J, 2007, HORM BEHAV, V51, P649, DOI 10.1016/j.yhbeh.2007.03.007
   Chamizo VD, 2011, BEHAV PROCESS, V88, P20, DOI 10.1016/j.beproc.2011.06.007
   Choi J, 2002, BRAIN COGNITION, V50, P116, DOI 10.1016/S0278-2626(02)00015-5
   Dabbs JM, 1998, EVOL HUM BEHAV, V19, P89, DOI 10.1016/S1090-5138(97)00107-4
   Daily JL, 2011, PLOS ONE, V6, DOI 10.1371/journal.pone.0027221
   Daugherty AM, 2015, CEREB CORTEX, V25, P3122, DOI 10.1093/cercor/bhu107
   Dettenborn L, 2013, PSYCHONEUROENDOCRINO, V38, P2373, DOI 10.1016/j.psyneuen.2013.03.011
   Devan BD, 2016, BEHAV PROCESS, V132, P34, DOI 10.1016/j.beproc.2016.09.009
   Driscoll I, 2005, HORM BEHAV, V47, P326, DOI 10.1016/j.yhbeh.2004.11.013
   Duff SJ, 2001, BRAIN COGNITION, V47, P470, DOI 10.1006/brcg.2001.1326
   Egan KR, 2012, J WOMENS HEALTH, V21, P1259, DOI 10.1089/jwh.2012.3522
   Gazova I, 2013, FRONT AGING NEUROSCI, V5, DOI 10.3389/fnagi.2013.00094
   Goeke CM, 2013, FRONT BEHAV NEUROSCI, V7, DOI 10.3389/fnbeh.2013.00005
   Gonzalez CLR, 2000, BEHAV BRAIN RES, V112, P43, DOI 10.1016/S0166-4328(00)00162-5
   Griksiene R, 2011, PSYCHONEUROENDOCRINO, V36, P1239, DOI 10.1016/j.psyneuen.2011.03.001
   Gron G, 2000, NAT NEUROSCI, V3, P404
   Guderian S, 2015, J NEUROSCI, V35, P14123, DOI 10.1523/JNEUROSCI.0801-15.2015
   Gur RC, 2000, BRAIN LANG, V74, P157, DOI 10.1006/brln.2000.2325
   Hamilton DA, 2007, J EXP PSYCHOL ANIM B, V33, P100, DOI 10.1037/0097-7403.33.2.100
   Hamilton DA, 2009, BEHAV PROCESS, V81, P154, DOI 10.1016/j.beproc.2008.12.003
   Hoeft F, 2008, J PSYCHIATR RES, V42, P253, DOI 10.1016/j.jpsychires.2007.11.010
   Jonasson Z, 2005, NEUROSCI BIOBEHAV R, V28, P811, DOI 10.1016/j.neubiorev.2004.10.006
   Kallai J, 2005, BEHAV BRAIN RES, V159, P187, DOI 10.1016/j.bbr.2004.10.015
   Kober SE, 2011, INT J PSYCHOPHYSIOL, V79, P347, DOI 10.1016/j.ijpsycho.2010.12.002
   Lavenex PB, 2010, BEHAV BRAIN RES, V207, P125, DOI 10.1016/j.bbr.2009.09.046
   Lawton CA, 2002, SEX ROLES, V47, P389, DOI 10.1023/A:1021668724970
   Leon I, 2016, BEHAV BRAIN RES, V306, P8, DOI 10.1016/j.bbr.2016.03.008
   Levy LJ, 2005, BEHAV NEUROSCI, V119, P853, DOI 10.1037/0735-7044.119.4.853
   MAEI HR, 2009, FRONT INTEGR NEUROSC, V3
   Maguire EA, 1998, SCIENCE, V280, P921, DOI 10.1126/science.280.5365.921
   Maguire EA, 2000, P NATL ACAD SCI USA, V97, P4398, DOI 10.1073/pnas.070039597
   Moffat SD, 2006, NEUROBIOL AGING, V27, P965, DOI 10.1016/j.neurobiolaging.2005.05.011
   MORRIS RGM, 1982, NATURE, V297, P681, DOI 10.1038/297681a0
   Mueller SC, 2008, PSYCHONEUROENDOCRINO, V33, P973, DOI 10.1016/j.psyneuen.2008.04.005
   Mueller SC, 2016, HORM BEHAV, V78, P121, DOI 10.1016/j.yhbeh.2015.10.018
   Mueller SC, 2008, BEHAV BRAIN RES, V193, P209, DOI 10.1016/j.bbr.2008.05.017
   Nowak NT, 2015, J ENVIRON PSYCHOL, V43, P136, DOI 10.1016/j.jenvp.2015.06.007
   Nowak NT, 2014, PSYCHONEUROENDOCRINO, V41, P13, DOI 10.1016/j.psyneuen.2013.12.003
   Padilla LM, 2017, PSYCHON B REV, V24, P582, DOI 10.3758/s13423-016-1118-2
   Penner MR, 2012, PROG NEUROBIOL, V96, P96, DOI 10.1016/j.pneurobio.2011.08.010
   Persson J, 2013, BEHAV BRAIN RES, V256, P219, DOI 10.1016/j.bbr.2013.07.050
   Piber D, 2016, NEUROBIOL LEARN MEM, V136, P139, DOI 10.1016/j.nlm.2016.10.006
   Rizk-Jackson AM, 2006, BEHAV BRAIN RES, V173, P181, DOI 10.1016/j.bbr.2006.06.029
   Sandstrom NJ, 1998, COGNITIVE BRAIN RES, V6, P351, DOI 10.1016/S0926-6410(98)00002-0
   Saucier DM, 2002, BEHAV NEUROSCI, V116, P403, DOI 10.1037//0735-7044.116.3.403
   Scheuringer A, 2017, FRONT PSYCHOL, V8, DOI 10.3389/fpsyg.2017.00381
   Skelton RW, 2006, BRAIN INJURY, V20, P189, DOI 10.1080/02699050500456410
   Skelton RW, 2000, J CLIN EXP NEUROPSYC, V22, P157, DOI 10.1076/1380-3395(200004)22:2;1-1;FT157
   van Gerven DJH, 2016, NEUROBIOL LEARN MEM, V132, P29, DOI 10.1016/j.nlm.2016.05.003
   van Gerven DJH, 2012, BEHAV NEUROSCI, V126, P465, DOI 10.1037/a0027992
   Vorhees CV, 2006, NAT PROTOC, V1, P848, DOI 10.1038/nprot.2006.116
   Voyer D, 2017, PSYCHON B REV, V24, P307, DOI 10.3758/s13423-016-1085-7
   WIEGRATZ I, 1995, CONTRACEPTION, V51, P341, DOI 10.1016/0010-7824(95)00098-U                                                    
   Woolley DG, 2010, BEHAV BRAIN RES, V208, P408, DOI 10.1016/j.bbr.2009.12.019
   [Anonymous], 2013, PLOS ONE, V8
NR 63
TC 0
Z9 0
U1 34
U2 34
PU ELSEVIER SCIENCE BV
PI AMSTERDAM
PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
SN 0166-4328
EI 1872-7549
J9 BEHAV BRAIN RES
JI Behav. Brain Res.
PD JAN 15
PY 2018
VL 336
BP 44
EP 50
DI 10.1016/j.bbr.2017.08.034
PG 7
WC Behavioral Sciences; Neurosciences
SC Behavioral Sciences; Neurosciences & Neurology
GA FK3JT
UT WOS:000413382100007
DA 2018-02-22
ER

EF